Brabazon, Edward Sir (c.1549–1625), 1st Baron Brabazon of Ardee , administrator, was the elder son, of the two sons and two daughters, of Sir William Brabazon (qv), vice-treasurer and thrice lord justice of Ireland, and his wife, Elizabeth, daughter of Nicholas Clifford of Holme, Kent. He was appointed to the Irish privy council in 1584, and was elected an MP for Co. Wicklow in 1585. He was knighted on 24 August 1595. From his father he inherited possession of the property of the dissolved monastery of St Thomas, near Dublin, and resided in the former abbey at Thomas-Court; these lands were confirmed to him on 13 March 1609. He also possessed English property in Warwickshire and Staffordshire, and was appointed sheriff of the latter county in 1606, though he saw this as interfering with his responsibilities in Ireland. In 1606 he was involved in plans to remodel part of Dublin castle, and was commended by Lord Deputy Chichester (qv) in 1610 as adept in surveying sites for houses and villages.
In 1613–15 he served as an MP for Bangor, and was appointed to the Munster presidential council on 20 May 1615. He was created Baron Brabazon of Ardee on 19 July 1616. He continued to serve as a councillor, and was recorded as lending money for the upkeep of the army in Ireland on several occasions. He died 7 August 1625 and was buried in St Catherine's, Dublin. He had married Mary, daughter of Edward Smith of Mitcham, Surrey, clerk of the green cloth, and had six sons and eight daughters, many of them dying in infancy. His heir, William, was created earl of Meath 16 April 1627.